phosphofructokinase, Platelet (PFKP) (C-Term) Peptid
PFKP
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN981621
Kurzübersicht für phosphofructokinase, Platelet (PFKP) (C-Term) Peptid (ABIN981621)
Target
PFKP
(phosphofructokinase, Platelet (PFKP))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- EWITAKLKEA RGRGKKFTTD DSICVLGISK RNVIFQPVAE LKKQTDFEHR
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PFKP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PFKP (phosphofructokinase, Platelet (PFKP))
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Hintergrund
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The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM, MIM 610681) and liver (PFKL, MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.
Alias Symbols: FLJ40226, PFK-C, PFKF
Protein Interaction Partner: DYNLL1,DMWD,GBAS,MCC,UBC,WIPI2
Protein Size: 784 -
Molekulargewicht
- 85 kDa
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Gen-ID
- 5214
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NCBI Accession
- NM_002627, NP_002618
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UniProt
- Q01813
Target
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